Research interests

My laboratory is broadly focused on developing and using computational approaches to understand life at the molecular level. I am particularly interested in exploring large-scale cancer genomics datasets, integrating different types of data (including protein structures) to gain insights into the molecular bases of cancer and immune system function.

Some current projects:

- effects of cancer mutations on protein function

- network-based analysis of cancer-mutated genes

- structural modeling of TCR/pMHC interactions in the immune system

- fragment-based discovery of drug targets

© Dario Ghersi 2021